Name | 3-Bromo-1-Amantane Carboxylic Acid |
Synonyms | 1-BroMo-3-carboxyadaMantane 3-bromo-1-adamantanecarboxylate 3-Bromo-1-Amantane Carboxylic Acid 1-BroMoadaMantane-3-carboxylic acid 3-BroMoadaMantane-1-carboxylic acid 3-Bromoadamantane-1-carboxylic acid 3-ADAMANTANECARBOXYLIC ACID, 1-BROMO- 3-broMo-adaMantaine-1-carboxylic acid 3-bromotricyclo[3.3.1.1~3,7~]decane-1-carboxylic acid (5R,7R)-3-bromotricyclo[3.3.1.1~3,7~]decane-1-carboxylate 3-Bromotricyclo[3.3.1.1~3,7~]decane-1-carboxylic acid, 1-Bromo-3-carboxyadamantane |
CAS | 21816-08-0 |
InChI | InChI=1/C11H15BrO2/c12-11-4-7-1-8(5-11)3-10(2-7,6-11)9(13)14/h7-8H,1-6H2,(H,13,14)/p-1/t7-,8-,10?,11?/m1/s1 |
Molecular Formula | C11H15BrO2 |
Molar Mass | 259.14 |
Density | 1.665±0.06 g/cm3(Predicted) |
Melting Point | 147 °C |
Boling Point | 354.2±25.0 °C(Predicted) |
Flash Point | 168°C |
Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 5.69E-06mmHg at 25°C |
Appearance | Solid |
Color | Pale Brown |
pKa | 4.35±0.40(Predicted) |
Storage Condition | 2-8°C |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
RTECS | AU4452500 |
Hazard Class | IRRITANT |
Application | 3-bromo-1-adamantanoic acid is an organic intermediate, which can be prepared by bromine adamantanoic acid. Adamantane and its derivatives can be used in medicine to make various specific drugs. |
preparation | slowly add adamantane formic acid to liquid bromine, under the action of anhydrous aluminum trichloride catalyst, stir reflux reaction at 20 ℃-10 ℃ for 48-60 hours, and then react at 20 ℃-30 ℃ for 5 hours to synthesize 3-bromo-1-adamantane formic acid. |